diff --git a/cmake/OpenCVCompilerOptimizations.cmake b/cmake/OpenCVCompilerOptimizations.cmake
index 52cc010fa7..45a536bb28 100644
--- a/cmake/OpenCVCompilerOptimizations.cmake
+++ b/cmake/OpenCVCompilerOptimizations.cmake
@@ -238,7 +238,7 @@ if(X86 OR X86_64)
   endif()
 
   if(NOT DEFINED CPU_DISPATCH)
-    set(CPU_DISPATCH "SSE4_1;AVX;FP16;AVX2" CACHE STRING "${HELP_CPU_DISPATCH}")
+    set(CPU_DISPATCH "SSE4_1;SSE4_2;AVX;FP16;AVX2" CACHE STRING "${HELP_CPU_DISPATCH}")
   endif()
 
   if(NOT DEFINED CPU_BASELINE)